show episodes
 
MyDNACoach.com, Jonny Deacon, explores and discusses the most current scientific innovations across the Health and Fitness industry, taking the guesswork out of fitness. Every week, Jonny interviews or reviews a new topic with leading industry professionals in order to build a better understanding of how people can optimize their health and fitness, through leveraging DNA testing, mindset development and expert coaching. Learn more at mydnacoach.com
 
The Victorian Institute of Sport (VIS) was established to assist the development of Victoria’s elite athletes by providing access to state-of-the-art sporting facilities and services. The VIS encourages its athletes to lead balanced lifestyles and as such also provides lifelong career and education support. The motto; Success in Sport and Life epitomises the purpose of the VIS.
 
Loading …
show series
 
Doc my heart is racing— Stop drinking—or so says this article in NEJM that found when they took 140 pts who severed from paroxysmal afib and who drank 17 drinks a week that when randomized to complete alcohol abstinence for 6 months there was significant reduction in afib recurrence.. how much of a difference?? 20% ABSOLUTE DIFFERENCE….. I have a r…
 
We stuck purely to the evidence. There was no evidence panel or committee to vote on the evidence like is often done by the American college of rheumatology and no expert opinion statements where their only citation is themselves like can be seen with the ACC. This was purely 100% evidence recommendations. So lets start try to make it quick because…
 
athlete heart covidhttps://www.the-scientist.com/news-opinion/college-athletes-experienced-heart-damage-after-covid-19-study-67929titiles like- “Images of the players’ hearts showed signs of inflammation consistent with myocarditis, a rare but potentially fatal condition.”“two dozen of Ohio State University players using cardiac magnetic resonance …
 
the thing about RCT is they are random and everything is equal. its why in table one of an RCT you should never see a pvalue because they are random and should be equal but in observational studies you see pvalues because it is not equal, it can’t be, its not random. In observational studies you try to account for all the confounders but you just c…
 
Finance ethics committee, big pharma with deep pockets, mafia like arrangements, and a patient with a 40% increase risk of ischemia myocardial events have in common?I will say todays podcast was inspired by a tweet, yes a tweet from Dr. john Mandrola and he said “I am embarrassed to have not (really) known the details of the rosiglitazone affair. T…
 
In this study of a cohort of German patients recently recovered from COVID-19 infection, CMR revealed cardiac involvement in 78 patients (78%) and ongoing myocardial inflammation in 60 patients (60%), independent of preexisting conditions,this was a freak out statement if I have ever heard of one I mean Covid is doing something directly to the hear…
 
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2768888Serial Bone Density Measurement and Incident Fracture Risk Discrimination in Postmenopausal WomenCarolyn J. Crandall, MD, MS1; Joseph Larson, MS2; Nicole C. Wright, PhD3; et al OBJECTIVETo assess whether a second BMD measurement approximately 3 years after the initial assessme…
 
Sometime I wonder how the world will change post covid- or how the board questions will change? And that is clearly seen in this article titled- Yip L et al. Serious adverse health events, including death, associated with ingesting alcohol-based hand sanitizers containing methanol — Arizona and New Mexico, May–June 2020. MMWR Morb Mortal Wkly Rep 2…
 
henry ford once said “failure is simply the opportunity to begin again, this time more intelligently”Designed to Fail? the Future of Primary CareJournal of General Internal Medicine (2020) Access to primary care has been shown to improve patient outcomes and lower cost although outcomes are debated the cost is not-its because we can be the jack of …
 
Characteristics and Strength of Evidenceof COVID-19 Studies Registeredon ClinicalTrials.gov Looked at ClinicalTrials.gov identified 1551 studies registered fromMarch 1, 2011, to May 19, 2020,Lets look at the gold standard RCTOf the 664 RCT (76.1%) were single center. PROBLEM! Weather analysis!Only half of the rct looked at clinical course with only…
 
Initiating Pharmacologic Treatment in Tobacco-Dependent Adults. An Official American Thoracic Society Clinical Practice Guidelinehttps://www.atsjournals.org/doi/full/10.1164/rccm.202005-1982STultimate take home- varenicline is first line!!For Tobacco-Dependent Adults in Whom Treatment Is Being InitiatedShould Treatment Be Started with Varenicline o…
 
https://www.youtube.com/watch?v=EBhEjYhVoZkGoggin K et al. Reductions in parent interest in receiving antibiotics following a 90-second video intervention in outpatient pediatric clinics. J Pediatr 2020 Jun 15; [e-pub]. (https://doi.org/10.1016/j.jpeds.2020.06.027)acute respiratory tract illnesses (ARTIs; cough, congestion, sore throat, and earache…
 
Orkaby AR et al. Association of statin use with all-cause and cardiovascular mortality in US veterans 75 years and older. JAMA 2020 Jul 7; 324:68. (https://doi.org/10.1001/jama.2020.7848) retrospective cohort study of about 327,000 patients (age, ≥75; mean age, 81; mostly white men) without prior statin use, without a prior cardiovascular event; in…
 
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2767257 still available for purchase in all states except New York, Maryland, and Ohio.Baby bumpers!!2038 adults were surveyed (176 were parents of a child aged <2 years). Positive beliefs about bumpers were that they “make the crib look better” (~65% agreed) and “help babies sleep” (~40%…
 
Effect of Dexamethasone in Hospitalized Patients with COVID-19: Preliminary Report (RECOVERY) trial is a randomized, controlled, open-label, comparison of dexamethasone 6 mg given once daily for up to ten days vs. usual care alone.2104 patients randomly allocated to receive dexamethasone were compared with 4321 patients concurrently allocated to us…
 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792273/Does Rewording MRI Reports Improve Patient Understanding and Emotional Response to a Clinical Report?Remember few weeks ago when I talked about 50% of people knew that broken bone and fracture were the same thing or that 1 in 5 pts couldn’t describe nonweight baring? Well this study looked o see …
 
Covid infohttps://melwy.com/blog/lancet-paper-on-chloroquine-is-overhyped-real-world-data-should-not-be-a-black-box So I couldn’t miss the largest observational study published to date on the effects of (hydroxy-)chloroquine, in 96 032 hospitalised Covid-19 patients, from an international registry comprising 671 hospitals in six continents:Surgisph…
 
Prostate Cancer Incidence 5 Years After US Preventive Services Task Force Recommendations Against Screening JNCI: Journal of the National Cancer Institute, djaa068,——Published: 20 May 2020https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2762575?guestAccessKey=1c75486d-f2a4-4e1b-ac99-25ca247be690&utm_source=silverchair&utm_medium=em…
 
Fox MT et al. Comparative effectiveness of antibiotic treatment duration in children with pyelonephritis. JAMA Netw vOpen 2020 May 1; 3:e203951. (https://doi.org/10.1001/jamanetworkopen.2020.3951) Rates of treatment failure did not differ significantly between the short and prolonged courses (11.2% and 9.4%). https://jamanetwork.com/journals/jama/f…
 
https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2762699Association Between Renin-Angiotensin System Blockade Discontinuation and All-Cause Mortality Among Persons With Low Estimated Glomerular Filtration RateThe answer was no; In a 5-year follow-up, ACE-I/ARB discontinuation was associated with an increased risk of both morta…
 
https://science.sciencemag.org/content/early/2020/04/24/science.abb5793read an interesting paper title- Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period. Science 14 Apr 2020.First, some basics but still things that I learned: • The two corona virus currently in cirulation are HKU1 and OC43 and they are seasonal- ma…
 
https://covid19treatmentguidelines.nih.gov/A National Institutes of Health panel has released new guidelinesagainst use of hydroxychloroquine plus azithromycin outside of clinical trials https://www.ncbi.nlm.nih.gov/pubmed/32001253Anaphylaxis—a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Developmen…
 
More cover 19 information based on antibody testing, pregnancy and pre-symptomatic spreadhttps://www.medrxiv.org/content/10.1101/2020.03.30.20047365v1.full.pdfhttps://www.nejm.org/doi/full/10.1056/NEJMc2009316?utm_source=The+Scope&utm_campaign=86f20fbd35-Weekly_Scope_Jan_12_2018_COPY_01&utm_medium=email&utm_term=0_809ad7d22b-86f20fbd35-180869057…
 
Remdesivir for compassionate use?? Recently published in the New England Journal of Medicine- Is this the COVID19 treatment we have all be hoping for.https://www.nejm.org/doi/full/10.1056/NEJMoa2007016https://jamanetwork.com/journals/jama/fullarticle/2764727?guestAccessKey=72e8a5f3-3754-4bf8-bb17-8c2f1cf358b0&utm_source=silverchair&utm_medium=email…
 
Treatment that works-- MASK!https://annals.org/aim/fullarticle/2764367/effectiveness-surgical-cotton-masks-blocking-sars-cov-2-controlled-comparisonHigh Velocity Nasal Insufflation (HVNI) Therapy Application in Management ofCOVID-19 Have patients wear a surgical mask—in this computer study it showed that mask do help but not necessarily mask on you…
 
https://www.nejm.org/doi/full/10.1056/NEJMoa1806515-- IVC filter after a severe injury = it is ok to wait 7 dayshttps://www.nejm.org/doi/full/10.1056/NEJMoa1904143antithrombotic therapy with afib after a pci and 1 year == just the DOAChttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31791-X/fulltextpolypill for primary prevention …
 
https://www.ncbi.nlm.nih.gov/pubmed/31550435 mono and athletes -- stick with 21 dayshttps://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32738 Hair Dye does not cause breast cancerhttps://jamanetwork.com/journals/jamanetworkopen/fullarticle/2753986?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110619mailing the HPV kit…
 
https://jamanetwork.com/journals/jama/article-abstract/2753909?guestAccessKey=03d877eb-6d48-476f-9487-aa6fbbd8a8d5&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=103019https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2754091https://academic.oup.com/eurheartj/advance-article/doi…
 
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2753986?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=110619 mailing hpv gets more people screened! Shocking!https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)32135-X/fulltext?rss%3Dyes patiromer might work but 70% of people don't need it ca…
 
https://insights.ovid.com/crossref?an=00006396-900000000-98602https://jamanetwork.com/journals/jama/article-abstract/2751887?guestAccessKey=8fa2f772-1ba4-40ff-9015-4fcb46d6829e&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jama&utm_content=olf&utm_term=091819https://www.ncbi.nlm.nih.gov/pubmed/14604741https://jamanetwork.com/jo…
 
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2748452 -- come one come all unless you are a kidney https://www.ncbi.nlm.nih.gov/pubmed/31054907 SURPRISE!! Women prefer to do self swab rather than clinician swabhttps://www.uspreventiveservicestaskforce.org/Page/Document/draft-recommendation-statement/hepatitis-c-screening1 If the…
 
https://www.ncbi.nlm.nih.gov/pubmed/30347032 Terbinafine adverse effects are rarehttps://www.ncbi.nlm.nih.gov/pubmed/31189511 Dulaglutide prevents MACE but at a high price taghttps://www.ncbi.nlm.nih.gov/pubmed/30853124 If you punch your buddy then get some buddy tapehttps://www.ncbi.nlm.nih.gov/pubmed/31076416 prediabetes gibes me a headache https…
 
Let's look at the numbers behind CAC! The best evidence is found here https://jamanetwork.com/journals/jama/fullarticle/2687224 but the largest study is found here https://www.sciencedirect.com/science/article/pii/S0735109715072253?via%3Dihub but in the end they use this https://en.wikipedia.org/wiki/Net_reclassification_improvement which might tri…
 
https://www.ncbi.nlm.nih.gov/pubmed/30874755 - ACC/AHA and ESC are still not evidence basedhttp://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.939.1670&rep=rep1&type=pdf -- only need to check every ten years-- it is the other risk factors that matter!https://www.ncbi.nlm.nih.gov/pubmed/26680162 Signal to noise is around 1 in 10 yrs…
 
https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2739056 not all guidelines are equal, think for yourself. Some guidelines even do harm when you actually look at the evidence. https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2740207 doacs and surgery what do you do-- low risk surgery stop one day prior an…
 
https://www.nejm.org/doi/full/10.1056/NEJMoa1813959 even when we dont know where the stroke is coming from- aspirin is still king all these years later https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)30840-2/fulltext Aspirin is such a king that is doesn't matter if you have a spontaneous brain bleed or intracerebral hemorrhage it…
 
Loading …

Quick Reference Guide

Copyright 2020 | Sitemap | Privacy Policy | Terms of Service
Google login Twitter login Classic login