This podcast is about Intensive care pharmacology and physiology. This is created to prepare intensive care trainees for their primary CICM exams. However, it will be of benefit to anyone who works in intensive care and keen to acquire new knowledge or want to refresh their memory.
The landscape of Intensive care is changing. In the era of evidence based medicine, we try to make best possible decision for our patients based on best available evidence. Every fortnight, Dr Swapnil Pawar & Dr Jose Chacko will bring you one hot topic in Critical care. If you want to stay up to date with recent evidence or learn how to critically evaluate the literature in critical care, this podcast is for you.
In this podcast series, we will meet educators around the globe to discuss various educational approaches and challenges that we face as an educator. An expert educator shares his/her insight and experience to help upcoming educators to progress in their career. This is a shared learning experience and we will like you to join this community to share your experience with other educators.
In this episode, we discuss what the importance of guidelines is, how they are formed and what does GRADE methodology involve.
In this episode, we dive deeper to understand how to interpret a meta-analysis, which is usually situated at the top of the pyramid of Evidence-based medicine.
In this podcast, we discuss the physics of ultrasound and Doppler along with the principles used in pulse oximetry and EtCO2 measurements.
In this podcast, we discuss the upsurge of the use of technology in Meded space during COVID-19 pandemic. Dr Eric Gantwerker from Chicago talks about the pros and cons of the different technological solutions emerged during this pandemic.
In this podcast, we discuss how one should interpret an RCT, which is considered as the gold standard while practising evidence-based medicine.
The role of steroids in COVID-19 has been endorsed after the publication of RECOVERY trial. However, whether we should change our practices based on just one trial was heavily debated. In this podcast, we discuss the role of steroid in COVID-19 in-depth and weigh all the available evidence on this topic.…
Prone positioning was first proposed in the 1970s as a method to improve gas exchange in ARDS. Subsequent observations of dramatic improvement in oxygenation with simple patient rotation motivated the next several decades of research. During COVID -19 pandemic, the debate on the utility of proning has been resurfaced. In this podcast, we dive deepe…
In this episode, we discuss the physiology of the central nervous system in depth.
Understanding of social determinants of health is important not only for budding medical professionals but also for medical educators. In this podcast, Dr Mobola Campbell-Yesufu from Northwestern university talks about the need to include this topic in all medical curricula across the globe.
In this podcast, we discuss a recently published landmark trial START-AKI trial. This trial explores the benefit of accelerated renal replacement strategy compared to standard strategy.
Join us in our Golden jubilee episode, where we discuss top 10 trials published in last two decades that helped to change the practices in Intensive care.
In this podcast, Maddi and I discuss various frequently asked questions on GI Physiology.
Join Dr. Eve Purdy from Canada to learn how to dissect the culture of your working environment through the lens of Anthropology. In this podcast, she describes simulation as a means to create moments of cultural compression and how that can be beneficial to evaluate and thus potentially modify the culture of the place.…
The cytokine storm, arising from a dysregulated host response, has captivated mainstream and scientific media in recent times with its possible role leading to poor outcomes in COVID-19. It is characterized by the release of mediators, including chemokines, interleukins, interferons, and tumor necrosis factors. In this podcast, we discuss the avail…
Tranexamic acid has been thought to be the wonder drug for stopping the active bleeding and has recently been proven life-saving in certain subgroups of patients. HALT_IT is another landmark trial that has evaluated the benefit of tranexamic acid in patients with acute GI bleeding. In this podcast, we discuss the implications of this landmark trial…
Recently published RCT in NEJM has raised more questions on the use of HCQ for post-exposure prophylaxis in COVID-19. This trial is more provocative than definitive. In this podcast, we discuss this trial in-depth and present our views on this topic.
The majority of guidelines for COVID-19 recommended against the use of steroids. However, RECOVERY trial has challenged this opinion by proving that low dose dexamethasone can actually improve the outcomes by both decreasing the mortality and facilitating early discharge from the hospital. In this podcast, we discuss the implications of this landma…
Haematology physiology is commonly asked in ICU primary exams. Join us in this podcast where we discuss haematology physiology in depth.
The routine use of Vit D in critically ill patients is debatable. The VIOLET trial published in NEJM in December 2019 has given us some clear answers on this topic. In this podcast, we discuss this trial in-depth to outline future directions on this topic.
Management of ARDS comprises of multi-modal approach that includes pharmacological and non-pharmacological interventions. The evidence on non-pharmacologic interventions is consistent. However, the benefit of pharmacological interventions is still debatable. In this podcast, we critically evaluate the role of neuromuscular blockade in ARDS.…
The recently published trial in JAMA has suggested that the treatment with convalescent plasma in COVID-19 is feasible and can be used as a potential treatment option in this devastating pandemic.
Professional identity formation (PIF) is a complex sociocultural process whereby medical students learn to think, feel, and act like physicians. In this podcast, Professor Mark Stephens from Pennsylvania helps us understand the concept of Professional identity formation (PIF) through the lens of mask making.…
In this episode, we discuss another landmark trial published in NEJM on the use of Remdesivir in COVID-19. This trial has raised more questions than providing answers.
In-depth understanding of Immune system for intensive care trainee is essential. In this podcast, Maddi & I talk about innate immunity, MHC proteins, the role of T & B lymphocytes along with hypersensitivity reactions.
In this podcast, we discuss multi-national registry data on the efficacy of chloroquine, hydroxychloroquine with or without macrolides in COVID-19 patients. This study has added significant information to our understanding of COVID-19 and has warned us against the use of the combination of HCQ and macrolides.…
COVID-19 pandemic has posed a very difficult challenge to the entire ICU community i.e. how to prevent transmission to health care workers while performing routine interventions in critically ill patients. This has forced us to unlearn the traditional ways and learn new ways of performing certain interventions in ICU. In this podcast, we discuss sp…
Translational simulation in the context of pandemic refers to the subset, which is oftentimes but not always in-situ simulation activity. This is really targeting a particular service outcome and involves going through essentially a quality improvement cycle of studying it, planning, doing something, restudying it, acting on that. COVID-19 pandemic…
Remdesisvir has thought to be the new CURE for COVID-19. In this podcast, we discuss the recent evidence available on the efficacy of Remdesivir in COVID-19.
The literature published from various countries has helped us to understand the disease pattern in COVID-19 pandemic. In this podcast, we discuss the key literature from New York, Italy, China and the UK.
COVID-19 has posed enormous challenges to the educator community. It's very important to maintain the mentor-mentee relationship during this pandemic. Dr. Ruth Gotian, Assistant Dean For Mentoring Academy at Weil Cornell medicine shares her tips on how to maintain and prosper this relationship in these difficult times.…
In this podcast, Maddi & I discuss hepatic physiology in depth.
In this episode, we summarise the key literature published in last week w.r.t novel therapies in COVID-19.
In this podcast, we discuss current controversies w.r.t treatment of COVID -19 patients and summarise the literature available till date.
In this podcast, we discuss how to manage critically ill patient diagnosed with COVID-19. This podcast based on current recommendations from various societies and the expressed views may change as recommendations change over time.
In this podcast, we discuss what is GFR, how kidneys handle water homeostasis and bicarbonate regulation in detail.
Vasopressor administration to maintain higher map in patients >65 years of age has become a dogma. In this podcast, we discuss recently published 65 trial which not only challenges this dogma but will definitely change our practices.
Oxygen is the most commonly used drug in Intensive care. However, the targets for oxygen therapy titration are arbitrary. In this podcast, we discuss the significance of hyperoxemia in intensive care patients.
In this podcast, Maddi & I discuss the obstetric physiology relevant to intensive care training.
Sedation in ICU is practised so commonly that thinking of any mechanically ventilated patient without sedation is impossible. This trial published in NEJM has challenged that dogma and showed us that Non-sedation in mechanically ventilated patients is feasible.
The accumulation of a positive fluid balance is a frequent occurrence in critically ill patients. As Paracelsus said, " All things are poisons, nothing is without poison. Only the dose permits something not to be poisonous." Like other drugs, it is the dose of fluids which makes them poisonous. In this podcast, we discuss the significance of de-res…
This Randomised controlled trial explored the role of HAT therapy in patients with septic shock admitted to ICU.