Exertional Heatstroke


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  • Heat Stroke is broadly defined as a core temperature above 104 F with central nervous system abnormalities following strenuous exercise or environmental heat. - Wilderness Medical Society.
  • Heat cramps, exhaustion, illness, stroke etc. are a spectrum of a single illness (systemic non drug related hyperthermia) rather than each being an individual entity.
    • Anhydrosis is not a reliable finding, and should not be used as a clinical guidepost.
  • An increase in blood temp triggers hypothalamic thermoregulation it increase blood flow to the skin – cutaneous vasodilation – blood shunts the the periphery to facilitate heat loss through sweating.
  • Renal and splanchnic perfusion is reduced.
  • Heat stroke produces an inflammatory response similar to that seen in sepsis.
  • Increased mucosal permeability from inflammatory mediators allows endotoxins from the gut to enter systemic circulation – leading to alterations in microcirculation, more endothelial and tissue injury, and impaired thermoregulation.
Prevention and Acclimatization
  • Acclimatization may be likened to receiving a "heat vaccine" with small steady doses of exertion in hot environments provoking an adaptive response within the body.
  • 1-2 hours of progressive, controlled, heat-exposed exertion per day for 10-14 days.
  • This adaptation may persist up to a month.
  • One bout of a heat stroke may reset thermoregulatory adaptations and increase risk for subsequent heat injury for months.
  • Hyperhydration has no effect on heat tolerance.
  • Forced hydration is ineffective and dangerous (hyponatremia risk).
Environmental Considerations
  • Wet Bulb Globe Temperature
    • "Composite" temperature factoring humidity, sun angle, apparent temperature, wind speed, and solar radiation.
    • Generally considered more accurate than the Heat Index, which is a function of temperature and humidity in shaded areas.
  • As the environmental temperature increases the body will incur a net heat gain through convective and radiative processes, leaving evaporative thermoregulation as the only cooling mechanism.
  • Some activities enhance heat transfer: Cyclist, swimmers, etc.
  • Increased metabolic demand and increased ambient conditions should lead to breaks in proportion to both.

Field Treatment Principles

  • Rapid, often empiric, cold water immersion is the gold standard treatment.
  • Rapid reversal of the condition is key: morbidity and mortality is directly associated with the duration of hyperthermia experienced by the patient.
  • If a patient is hyperthermic and has AMS, empiric cooling should not be delayed to obtain a temperature – or if temperature is less than 104 F, it should not deter you from aggressive cooling measures.
  • Naturally, manage ABCs as needed.
  • Treatment on scene is preferred over rapid transport.
Cold Water Immersion Therapy
  • CWIT is the gold standard of treatment, and usually involves placing a patient's entire body (with airway protection measures in place) in a tub or trough of cold water.
  • CWIT is two times more effective in heat transfer than spraying cool water over the body.
  • Hindrance of cooling in the setting of EHS due to shivering has been physiologically refuted.
Other Cooling Methods
  • If CWIT is not available, repeated dousing of cold water over the patient is "next best".
  • Ice Sheets placed over the patient's body and exchanged every 2-3 minutes is an approach often adapted by the military where carrying large troughs of ice water is not optimal.
  • Axillary or inguinal placement of chemical cold packs or ice is not effective.
  • Be creative! The goal is to get large volumes of water over the patient or place the patient in a body of water to maximize the effect of convective cooling.

Temperature Monitoring

  • Rectal and/or esophageal temperature monitoring is the gold standard.
  • Oral, axillary, or skin temperature readings are highly likely to be inaccurate.
  • Temperature monitoring is not required to initiate therapy, but may be helpful to guide therapy or consider other differential diagnoses.

28 episodes