My DNA Coach Podcast I Jonny Deacon I Health I Fitness I DNA Testing I Blood Testing |A.I |DEXA I Kolbe A Index | Personal Training
EPISODE 138 - DNA FOCUS - FABP2
Manage episode 192796866 series 1184045
This week we turn our attention to FABP2, a gene that appears in both the carbohydrate and saturated fat parts of our reports. This gene creates a protein called Fatty Acid Binding Protein-2, which is found in our small intestines. FABP2 binds to the various different fatty acids, and allows them to be absorbed into the body.
The single nucleotide polymorphism (SNP) that we are interested in occurs when an alanine nucleotide is swapped for a threonine nucleotide; this substitution causes the protein to become more efficient. So efficient, in fact, that it doubles the speed at which we absorb these fats, leading to an increase of fat in the blood stream.
This genotype is not associated with an increased sensitivity to saturated fats or refined carbohydrates.
A single copy of the A allele is associated with a moderately increased sensitivity to saturated fats and refined carbohydrates.
Two copies of the A allele of FABP2 means that this genotype is associated with a significantly increased sensitivity to both saturated fats and refined carbohydrates.
Resources & Studies Mentioned