EPISODE 141 - DNA FOCUS - CAT & GPX1

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This week we look at two genes that form part of our antioxidant needs section of the our nutrition reports, called CAT and GPX1. The gene that carries the most weight in this section is SOD2, which we have looked at previously in this series. If you can’t remember that far back, SOD2 is an antioxidant enzyme, and small changes in the SOD2 gene can lead to that enzyme working better or worse, which can increase how much of the antioxidant nutrients you require. CAT and GPX1 play a supportive role here.

CAT

GPX1

CC

Good enzyme activity – standard antioxidant intake required.

Good enzyme activity – standard antioxidant intake required.

CT

Moderately reduced levels of enzyme activity – ensure slightly higher intake of antioxidants.

Moderately reduced levels of enzyme activity – ensure slightly higher intake of antioxidants and selenium.

TT

Lowest level of enzyme activity – should increase intake of antioxidants.

Lowest level of enzyme activity – should increase intake of antioxidants, especially selenium.

Resources & Studies Mentioned

https://www.ncbi.nlm.nih.gov/pubmed/16538174

169 episodes