Week 10 NFL Picks: Bills-Cardinals, Seahawks-Rams, Vikings-Bears, Locks & Upsets

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In this week's episode of The Spread, Mike Cole, Ricky Doyle and Andre Khatchaturian give their against-the-spread picks for the biggest games of Week 10 including Buffalo Bills vs. Arizona Cardinals, Seattle Seahawks vs. Los Angeles Rams and Minnesota Vikings vs. Chicago Bears.

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