Episode 90: Mild Cognitive Impairment (MCI) : 3 words you never want to hear.


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By Dr. Karl Goldkamp. Discovered by Player FM and our community — copyright is owned by the publisher, not Player FM, and audio is streamed directly from their servers. Hit the Subscribe button to track updates in Player FM, or paste the feed URL into other podcast apps.

Most of us have some idea what dementia is. Though we toss the word ‘demented’ around as a put down, Dementia, and Alzheimers experienced up close is difficult to witness. In part why it is so difficult to watch others go through the decline is because much of it can be avoided entirely by adopting a Low Carb High Fat Ketogenic diet. If there was one specific condition that is most improved by ketones, this would be it. In fact, unlike other conditions that can be improved by a ketogenic diet, taking ketones directly for Alzheimers or dementia has become a gold mind for certain companies that are now in business of creating them. The market for both LCHF Ketogenic diet and for ketones is based on two truths, the rate of Alzheimers is at an all time high and will just increase, and Mild Cognitive Impairment is happening at a younger and younger age. Both demographics can be addressed fairly easily. Listen in to hear how we do that.
Sweethearts Forever. Then Came Alzheimer’s, Murder and Suicide.“They were absolutely soul mates.” 12-30-2019
Stephen Cunnane - April 26, 2018


Dr. Cunnane 2016-7Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s Disease


Ketones are the brain’s main alternative fuel to glucose and brain ketone uptake is still normal in MCI and in early AD, which would help explain why ketogenic interventions improve some cognitive outcomes in MCI and AD. We suggest that the brain energy deficit needs to be overcome in order to successfully develop more effective therapeutics for AD. At present, oral ketogenic supplements are the most promising means of achieving this goal.
A ketogenic drink improves brain energy and some measures of cognition in mild cognitive impairment
Emulsification Increases the Acute Ketogenic Effect and Bioavailability of Medium-Chain Triglycerides in Humans: Protein, Carbohydrate, and Fat Metabolism.

Emulsification increased the ketogenic effect and decreased side effects in a dose-dependent manner for single doses of MCTs ≤30 g under matching conditions. Further investigation is needed to establish whether emulsification could sustain ketogenesis and minimize side effects and therefore be used as a treatment to change brain ketone availability over a prolonged period of time.
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Until next time

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