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16 Minutes on the News is a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends? About the a16z Podcast: Discusses tech and culture trends, news, and the future -- especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This ...
 
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In today’s episode we have two short segments, both on bioscience topics:[0:00] Moderna has started clinical trials for a flu vaccine, called mRNA-1010, that is based on the same mRNA technology that Moderna and Pfizer used for their COVID vaccines, and that several other companies including Sanofi and Glaxo all are actively working on for the infl…
 
We’ve been running Software Daily for 6 years. When we started it back in 2015, the goal was to create a software engineering podcast that was 60% as good as Software Engineering Radio, but aired with 5x the frequency. 5 shows per week, 50 weeks per year, 5 ads per show, means 1,250 advertising spots. We are a two sided marketplace for podcast ads …
 
Given recent news of drug company settlements, calls to action, policy moves, and more, this episode is a rerun of one of our very early explainers (episode #4 of 16 Minutes, 2019) on the opioid crisis. Bio experts and a16z general partners Jorge Conde and Vijay Pande discuss on 16 Minutes (our shortform show where we discuss the headlines, tease a…
 
Welcome to 16 Minutes, the a16z show where we talk about tech trends in the news, what’s hype and what’s real, and the long arc of innovation. In today's episode we’re talking about the latest developments and trends in cybercrime – including the trends of ransomware, and, attacks on physical infrastructure. First (0:00 - 6:07), we have the recent …
 
Given recent buzz and ongoing debates around the Endless Frontiers Act -- which some have described as “the most important piece of legislation no one's heard of” -- this episode is a rerun of an episode from last year, recorded after said act was initially unveiled. The short discussion covers the broader topic and theme of funding science and inn…
 
Playing out against the backdrop of a global pandemic (including recent massive surges in regions around the world) is the news that came out a week ago that a candidate "malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal”. While the findings are still in preprint with The Lancet, the resulting buzz and phrases quoted included…
 
In this week’s episode of 16 Minutes, our show where we cover tech trends in the news — and also cover themes from company developer and innovation events! — we focus on the latest coming out of Apple’s event this week. The company announced a bunch of things, ranging from new device colors and form factors to podcast services, but in this episode …
 
We have two brief segments in today’s episode: News and analysis of the Johnson & Johnson COVID vaccine pause, and the widespread hack of Microsoft Exchange Servers across the country (and the dramatic and unusual steps the FBI took in response). Johnson & Johnson: Federal health officials last week revealed that six women who received the vaccine …
 
This deep-dive -- one of our occasional 2-4X explainer episodes on 16 Minutes; (past such episodes have covered everything from Section 230 and Tiktok to GPT-3 and the opioid crisis) -- teases apart what's hype/ what's real -- and the what, where, how, why, who, and other questions top of mind around all things NFTs: what NFTs (non-fungible tokens)…
 
Today on our news analysis show 16 Minutes — since this show is all about teasing apart what’s hype/ what’s real and where we are on the long arc of innovation — we're taking a quick pulse-check with the experts on just where we are with the COVID vaccine rollout in the U.S. Our experts today are Dr. Bob Wachter, the Chair of the Department of Medi…
 
In today's episode of our news analysis show 16 Minutes, our topic is the ongoing buzz and the mixed news around the Johnson & Johnson vaccine, which was the third vaccine for COVID approved under Emergency Use Authorization by the FDA just a few weeks ago. Johnson & Johnson reported it as “the first single shot vaccine” and as having 85% efficacy …
 
In this week’s episode of 16 Minutes, our show where we talk about tech trends in the news, what’s hype/ what’s real, and where we are on the long arc of innovation, the topic is semiconductors – specifically, the ongoing global shortage that began last summer and has intensified in recent weeks. So much so, that the U.S. president signed an execut…
 
In this week’s episode of 16 Minutes — where we talk about tech trends in the news, what’s hype/ what’s real, and where we are on the long arc of innovation — the topic is NFTs ("non-fungible tokens"); specifically, the news that Christie’s has become the first major auction house to offer a purely digital artwork tied to an NFT or “non-fungible to…
 
We have two brief segments — taking up less than 16 Minutes! — in this week’s episode of "16 Minutes," where we talk about tech trends in the news, what’s hype/what’s real, and where we are on the long arc of innovation. Both segments touch on trends in gaming/ online worlds and entertainment — both now and "next." First, Steam China: Steam — the c…
 
Amazon just announced this week that its founder and CEO Jeff Bezos "will transition to the role of Executive Chair in the third quarter of 2021 and [CEO of Amazon Web Services] Andy Jassy will become Chief Executive Officer at that time". So in this episode of 16 Minutes -- our show where we talk about tech trends in the headlines, what's hype/ wh…
 
In this special “3x”-long episode of our (otherwise shortform) news analysis show 16 Minutes -- past such 2-3X explainer episodes have covered section 230, Tiktok, GPT-3, the opioid crisis, more -- we cover the SolarWinds hack, one of the largest (if not the largest!) publicly known hacks of all time... and the ripple effects are only now starting …
 
We've got segments on artificial intelligence and IPO innovation in today's episode of 16 Minutes, where we take a look at the news and what it means for the long arc of innovation. In the first segment (0:00): Take the surrealistic images of Salvador Dali and cross them with Pixar's animated film Wall-E and you've got ... Dall-E! It's a new neural…
 
All about section 230 of the Communications Decency Act -- what does and doesn't it say? How does this law play out against broader questions and debates around platforms, content moderation, and free speech? This conversation between Mike Masnick (founder and editor in chief of Techdirt) and a16z editor in chief Sonal Chokshi was originally publis…
 
We're covering two trends in this week’s episode of "16 Minutes," where we talk about the news, tech trends, and the long arc of innovation: #1 FinCEN, the Treasury Department's financial crimes enforcement arm, proposed a new rule targeting cryptocurrency holders’ ability to transact using self-hosted wallets. These are software applications for s…
 
We're back to covering multiple items on our show 16 Minutes -- which covers the news, occasional explainers, and teases apart what's hype/ what's real -- as well as where we are on the long arc of innovation: #1 Hackers spied on U.S. Treasury emails and other federal agencies through malware installed (indirectly via a third-party provider) over a…
 
In this episode of our show 16 Minutes -- where we talk about the headlines, and where we are on the long arc of tech trends -- we cover the news around Google DeepMind's AlphaFold system for predicting the 3-D structure of proteins outperforming 100 teams across 20 countries in the 14th Community Wide Assessment on the CASP (Critical Assessment of…
 
[simplecast-embed src="https://16minutes.simplecast.com/episodes/16mins-transparency-in-coverage-rules-cms-hhs-healthcare-pricing-cost-patients-payers-hospitals-comparison-competition?dark=true"] The Centers for Medicare & Medicaid Services (CMS) issued the latest in a series of “historic" rules a few weeks ago; the controversial rules -- which hav…
 
We cover the latest coming out of Apple’s event last week, where they announced the first new lineups of devices based on Apple Silicon M1 chips, which officially came out today. And since there’s already plenty of analysis on performance, benchmarks, and more, we cover the big picture: Apple’s moving away from Intel chips, and to their own chips (…
 
A vaccine for COVID seems to be (almost) here... or is it? What's hype/ what's real beyond the headlines (and beyond the press release), when it comes to the announcement earlier this week from Pfizer and BioNTech that their vaccine candidate was found to be more than 90% effective in preventing COVID-19? Of course, this was just the first interim …
 
Aliens are among us. Well, the online multiplayer game Among Us is -- a murder mystery set in space, where the group must figure out who the alien imposter is (a variation of party games like Werewolf or Mafia) -- has seemingly suddenly become very popular. And not just because a major politician livestream-played it earlier this week, which is wha…
 
"It's CRISPR!" This week, the Nobel Prize in Chemistry was awarded to scientists Emmanuelle Charpentier and Jennifer Doudna (also an a16z co-founder, of Scribe Therapeutics), for the development of the CRISPR/Cas9 method for genome editing -- a technology that's "had a revolutionary impact on the life sciences, is contributing to new cancer therapi…
 
We cover the latest news since Nvidia (maker of GPUs among other things) announced its intent to acquire Arm (provider of silicon IP for system-on-chips inside billions of devices), arguing that "This combination has tremendous benefits for both companies, our customers, and the industry." But how so, when critics are worried about channel conflict…
 
In one of our special "2x" episodes of 16 Minutes (32ish minutes;) -- our show where we quickly cover the headlines and tech trends, offering analysis, frameworks, explainers, and more -- we cover the algorithm that powers TikTok, the short video-sharing platform that grabbed massive marketshare in cultures and markets never experienced firsthand b…
 
We cover the latest coming out of Apple's event yesterday, focusing on their new watches (including a lower price model); new sensors (including blood oxygen); and services for healthcare. Is always-on, (relatively) low-cost, passive monitoring for fitness and mainstream consumers really, finally the wedge into data for clinical applications as wel…
 
In this episode of 16 Minutes, we cover the recent news around the FDA's Emergency Use Authorization approval of Abbott Lab's latest COVID-19 test, which takes 15 minutes and will cost $5. At that speed and price point -- as well as the fact that it doesn't require lab equipment at point of care -- it should definitely increase testing capacity, ma…
 
In this episode of 16 Minutes -- our show where we cover recent headlines; tease apart what's hype/ what's real; and help orient where we are, trends-wise, on the long arc of innovation -- we cover the merger of Teladoc and Livongo, which was announced just a few days ago. The $18.5B deal is a big deal not just because of the dollars and validation…
 
In this special "2x" explainer episode of 16 Minutes -- where we talk about what's in the news, and where we are on the long arc of various tech trends -- we cover all the buzz around GPT-3, the pre-trained machine learning model that's optimized to do a variety of natural-language processing tasks. The paper about GPT-3 was released in late May, b…
 
This holiday break episode of 16 Minutes on the News (#36) covers two timely and still developing-news topics: #1 The National Science Foundation could rebrand as the National Science AND Technology Foundation -- as well as get up to $100B more in funding for 10 focus areas among other things -- if a new bipartisan proposal called the "Endless Fron…
 
A number of features were announced at Apple's WWDC/ Worldwide Developers Conference this week, but this episode of 16 Minutes on the News focuses on just one: Apple's "App Clips" coming to iOS14. Because App Clips -- small, lightweight, fast, parts of a full app that can quickly execute just one specific action for users in context, when and where…
 
The FDA just approved the first ever videogame that can now be legally marketed and prescribed as a medicine. It's a game called EndeavorRX (formerly known as Project EVO and developed by Akili Interactive based on technology licensed from a neuroscience lab at the University of California San Francisco) -- and is for 8-12 year olds with Attention …
 
At last week's Snap Partner Summit, a number of announcements -- including a navigation redesign and Bitmoji for Games -- have broader implications for the gaming industry and beyond. Especially when such messaging games, built on HTML5 and "mini programs" or apps-within-apps (as discussed by Connie Chan in context of WeChat and more), merge the ke…
 
In this special "2x" episode (#32) of our news show 16 Minutes -- where we quickly cover the headlines and tech trends, offering analysis, frameworks, explainers, and more -- we cover the tricky but important topic of Section 230 of the Communications Decency Act. The 1996 law has been in the headlines a lot recently, in the context of Twitter, the…
 
While governments, policymakers, and employers around the world are all figuring out how to reopen the economy, contact tracing -- which includes identifying and warning contacts of exposure in order to stop chains of transmission -- is a key strategy for preventing further spread of a disease like COVID-19. But approaches vary from manual to autom…
 
As calls for better, faster, cheaper, portable testing for COVID-19 disease are heard around the world -- given the important role of test-trace-isolate in re-opening the economy! -- the FDA recently issued an Emergency Use Authorization (EUA) for a CRISPR-based diagnostic. It's the first authorized use of CRISPR technology for an infectious diseas…
 
Zoom has not only experienced unprecedented, rapid growth (from 10M to 200M daily active users) due to the coronavirus pandemic and shelter-in-place -- but is also seeing a shift in use cases from primarily enterprise to more consumer as well. At the same time, there have been several security issues and concerns around Zoom, including "zoombombing…
 
If the best way to know whether a medicine is effective is through a clinical trial, then where does (and doesn't) real-world data and real-world evidence come in? The topic is always top of mind in drug development, with additional focus as of 2016 thanks to the 21st Century Cures Act -- but is especially heated lately given recent concerns and cl…
 
The U.S. Federal Reserve recently made a range of moves -- from cutting interest rates to near zero (which it also did in the 2008 financial crisis) and using other tools -- to support "the flow of credit to households and businesses, thereby promote its maximum employment and price stability goals" during this current pandemic and public health cr…
 
This episode of 16 Minutes on the News covers the U.S. Department of Health and Human Services' "historic rules" to provide patients more control of their data. They've been a long time coming, and despite recent fights over them, the final rules are now finally here as of this week. So in this short but deep dive, a16z bio experts -- general partn…
 
This episode of 16 Minutes on the news covers: Google could bring Steam support to Chrome OS, according to an earlier unconfirmed report, and what that could mean for the broader gaming ecosystem, developers as well as devices -- with a16z general partner Andrew Chen and Jonathan Lai on the consumer team; New York restaurants and retail establishme…
 
This episode of 16 Minutes on the news covers: all the recent fintech acquisitions! from Intuit announcing it's acquiring Credit Karma this week to Morgan Stanley announcing it's acquiring E-trade last week to Visa acquiring Plaid last month, and so on -- what’s going on, why, and why now? -- with a16z general partner Anish Acharya; recent hearing …
 
This episode covers the latest updates since our previous deep-dive on the novel coronavirus outbreak. We cover the latest developments -- new name, new declarations, new numbers, new definitions -- as well as: practical implications for the U.S. healthcare system given how it works today, and where we might go in the future -- with a16z general pa…
 
This episode of 16 Minutes on the news covers: FICO credit score changes, what are they, do they matter? -- with a16z fintech general partners Angela Strange and Anish Acharya; electronic health record provider Epic's letter urging hospitals to oppose government regulations that would make it easier for patients and companies to access medical info…
 
This episode of 16 Minutes on the news from a16z is all about the recent coronavirus outbreak -- or rather, a new type of coronavirus called 2019-nCoV for 2019 novel coronavirus. Since it's an ongoing and fast-developing news cycle, we take a quick snapshot for where we are, what we know, and what we don't know, and discuss the vantage point of whe…
 
This episode of our news show teases apart what was just a concept, what's near from the annual Consumer Electronics Show (CES 2020). Board partner Steven Sinofsky (in conversation with Sonal Chokshi) takes us on a quick tour of the based on his annual field trip report from the floor. Topics covered include: folding screens and 8K displays 5G, wi-…
 
In this 19th episode of our news show, where we cover recent headlines from our vantage point in tech, we cover the following news items (in conversation with Sonal Chokshi): recent moves to regulate artificial intelligence (AI) software including the White House's recent guidance (and op-ed from the U.S. CTO) on AI in general, as well as limits to…
 
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