Does Red Meat Accelerate Aging, with David Sinclair PhD - UPDATE and REPOST


Manage episode 317817894 series 2505553
By Paul Saladino, MD, Paul Saladino, and MD. Discovered by Player FM and our community — copyright is owned by the publisher, not Player FM, and audio is streamed directly from their servers. Hit the Subscribe button to track updates in Player FM, or paste the feed URL into other podcast apps.

David Andrew Sinclair, PhD is an Australian biologist and professor of genetics. He is also a co-director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, and is known for his research on aging with a focus on epigenetics.

Time Stamps:

0:35:27 Podcast begins with David Sinclair

0:36:25 Is when we eat more important than what we eat?

0:38:45 What is the connection between time restrictive eating and longevity?

0:43:54 What causes us to age?

0:45:46 Epigenetic change.

0:52:03 What causes DNA breaks?

0:55:28 What plant foods create DNA breaks?

0:57:13 PARP enzymes

1:00:46 Where does NAD come from? How do we make it? What enzymes use it?

1:04:50 NAD recycling pathway.

1:12:13 Sirtuins.

1:24:14 What are the other longevity genes? (AMP kinase and mTOR) How are they connected to sirtuins?

1:31:50 Does being in a ketogenic state increase NAD?

1:40:30 Xenohormesis and plant molecules.

1:45:50 Resveratrol trials.

1:51:55 mTOR.

1:57:25 David’s thoughts on animal protein.

2:04:03 Meat consumption in relation to the environment and regenerative agriculture.

2:11:28 Where to find David Sinclair.

David’s info:

Instagram: @davidsinclairphd

Twitter: @davidasinclair


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