Understanding Retroviruses with Dr. Melissa Kane

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By UPMC Children's Hospital of Pittsburgh and UPMC Children’s Hospital of Pittsburgh: Leader in pediatric medicine and. Discovered by Player FM and our community — copyright is owned by the publisher, not Player FM, and audio is streamed directly from their servers. Hit the Subscribe button to track updates in Player FM, or paste the feed URL into other podcast apps.

The central focus of the Kane Lab is understanding the genetic and immunological basis for protective antiviral immune responses, as well as the molecular details underlying the direct inhibition of retroviral replication by restriction factors. Dr. Kane’s lab utilizes both in vitro and in vivo tools to investigate intrinsic, innate, and adaptive immune responses to retroviral infection. The research is centered around three questions: What allows some individuals to restrict or control retroviral replication? How do retroviruses counteract host defenses? And what are the features of successful anti-retroviral immune responses?

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