What Are Apolipoproteins?


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By Michael Chapman and Genova Diagnostics. Discovered by Player FM and our community — copyright is owned by the publisher, not Player FM, and audio is streamed directly from their servers. Hit the Subscribe button to track updates in Player FM, or paste the feed URL into other podcast apps.

When assessing risk for cardiovascular disease, most clinicians focus on the concentration of low-density lipoproteins (LDL) also known as ‘bad’ cholesterol, and high-density lipoproteins (HDL) or ‘good’ cholesterol. Though this information is helpful, it’s only part of the picture when it comes to risk. Apolipoproteins are surface proteins found on all cholesterol molecules. They not only contribute to cholesterol structure, but also help to regulate enzymes responsible for lipid metabolism, assist in reverse cholesterol transport, and direct the distribution of fuel throughout the body.

In today’s episode, we discuss apolipoproteins, their function, and why measuring them can be a game-changer when it comes to cardiovascular risk assessment.

Today on The Lab Report:

  • 3:45 What is an Apolipoprotein?
  • 6:40 Particle number and particle size
  • 9:00 Apolipoprotein A-1 and B
  • 11:45 Better Know a Biomarker: Apolipoprotein B/A-1 Ratio
  • 15:30 Lipoprotein (a) - Lp(a)
  • 17:05 Question of the Day?
    • What medications/supplements influence the Cardio Check?

Additional Resources:

Cardio Check

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